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B-hα4β7 mice
Strain Name
C57BL/6-Itga4tm1(ITGA4)BcgenItgb7tm1(ITGB7)Bcgen/Bcgen
Common Name  B-hα4β7 mice
Background C57BL/6 Catalog number 111913
Related Gene 

integrin subunit alpha 4, CD49D, IA4; integrin subunit beta 7, Ly69

Protein expression analysis-DCs 


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Strain specific ITGA4 and ITGB7 expression analysis in homozygous B-hα4β7 mice by flow cytometry.  Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hα4β7 mice (H/H; H/H). Mouse ITGA4 and ITGB7 were exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 and ITGB7 were exclusively detectable in homozygous B-hα4β7 mice.

Protein expression analysis-NK cells 


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Strain specific ITGA4 and ITGB7 expression analysis in homozygous B-hα4β7 mice by flow cytometry.  Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hα4β7 mice (H/H; H/H). Mouse ITGA4 and ITGB7 were exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 and ITGB7 were exclusively detectable in homozygous B-hα4β7 mice.

Protein expression analysis-Monocytes 


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Strain specific ITGA4 and ITGB7 expression analysis in homozygous B-hα4β7 mice by flow cytometry.  Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hα4β7 mice (H/H; H/H). Mouse ITGA4 and ITGB7 were exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 and ITGB7 were exclusively detectable in homozygous B-hα4β7 mice.


Protein expression analysis-Macrophages 

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Strain specific ITGA4 and ITGB7 expression analysis in homozygous B-hα4β7 mice by flow cytometry.  Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hα4β7 mice (H/H; H/H). Mouse ITGA4 and ITGB7 were exclusively detectable in wild-type C57BL/6 mice. Human ITGA4 and ITGB7 were exclusively detectable in homozygous B-hα4β7 mice.