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2025
AACR 2025: NKC and KIR humanized mice: a powerful tool to develop NK-targeting drugs
2025
AACR 2025: Generation of humanized C1Q mice for antibody-mediated CDC therapy research
2025
AACR 2025: The trispecific T cell engager platform enhances T cell function and therapeutic efficacy via integrated 4-1BB VHH antibody co-stimulation
2025
AACR 2025: RenBiologics- a fully human antibody library generated by RenMice facilitates the development of antibody drugs
2025
AACR 2025: Preclinical study of bispecific antibody drug conjugates (bsADCs) targeting DLL3 and SEZ6 demonstrated potent anti-tumor activity in small cell lung cancer (SCLC) xenograft models:
2025
AACR 2025: Discovery of a highly potent fully human VEGF VHH antibody from RenNano transgenic mice that exhibits a superior blocking activity on VEGF function
2025
AACR 2025: Development of fully human TCR-mimic antibodies targeting intracellular tumor antigens using humanized RenTCR-mimic transgenic mice
2025
AACR 2025: Development of a human immune system reconstituted mouse model without the function of FcγRs expressed on mouse innate immune cells
2025
AACR 2025: Development and validation of humanized HLA-A11.1 mouse model for preclinical evaluation of novel peptide vaccines
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