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B-Dmp1-iCre mice
Strain Name


C57BL/6-Dmp1tm1(icre)Bcgen/Bcgen


Stock No. 


110124


Common name


B-Dmp1-iCre mice


Gene symbol and name 


Dmp1 dentin matrix protein 1


Strain of origin

C57BL/6

Chromosome  5
Coat color Black Dietary information

Growth and reproduction diet for experimental mice

Results of agarose gel electrophoresis

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Gel image of PCR products. PCR products are separated by gel electrophoresis on a 2% agarose gel. PC: samples used for PCR were collected from heterozygous mice; WT: samples used for PCR were collected from wild type mice; H2O: blank control.


Phenotype Analysis

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NPY deletion in osteocytes rather than in osteoblasts of Dmp1-iCre (Dmp1-iCre was purchased from Biocytogen Co. Ltd., Beijing, China); Npyfl/fl mice, was confirmed by western blotting for the protein lysates of the isolated osteocytes and osteoblasts (A).

NPY protein expression was much lower in the bone marrow-depleted femur homogenates, but not in the whole bone marrow cells, the whole brain lysate, and the NPY-abundant hypothalamus, of 4-month-old Dmp1-iCre; Npyfl/fl mice than that of Npyfl/fl littermates (C).

 (source: Yan Zhang, et al., 2021)