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B-hMSLN mice
Strain Name

C57BL/6N-Mslntm1(MSLN)/Bcgen

Common Name 

B-hMSLN mice

Background C57BL/6N Catalog number

111129

Related Genes 

MPF, SMRP


Protein expression analysis



Strain specific MSLN protein expression analysis in wild-type mice and B-hMSLN mice by western blotting. Mouse MSLN was detectable in heterozygous B-hMSLN mice (H/+) and wild-type mice (+/+). Human MSLN was detectable only in B-hMSLN mice (H/+).


MSLN expression analysis by IHC


from clipboard


Representative mesothelin expression in lung tissues of B-hMSLN mice by IHC. Tissues were stained with antibodies specific for human MSLN (A, B) or anti-Rabbit IgG antibody (C). Membranes show human MSLN positive in homozygous B-hMSLN mice. The data was obtained from a partner. Original magnification ×20. Abbreviations: IHC, immunohistochemistry.