B-hCD89 mice
| Strain Name |
C57BL/6N-Gt(ROSA)26Sortm1(CD11b-FCAR)Bcgen/Bcgen
|
Common Name | B-hCD89 mice |
| Background | C57BL/6N | Catalog number | 110864 |
| Aliase | CD89; FcalphaRI; CTB-61M7.2, FCAR, Fc fragment of IgA receptor | ||
mRNA expression analysis
Strain specific analysis of CD89 gene expression in wild type (WT) mice and B-hCD89 mice by RT-PCR.
Human CD89 mRNA was detectable only in splenocytes of homozygous B-hCD89 mice (H/H) but not WT mice (+/+).
Strain specific CD89 expression analysis in homozygous B-hCD89 mice by flow cytometry.
Spleen, bone marrow and blood were collected from wild type (WT) mice (+/+) and homozygous B-hCD89 mice (H/H), and analyzed by flow cytometry with species-specific anti-CD89 antibody. Human CD89 was exclusively detectable in NK cells of homozygous B-hCD89 mice (H/H).
Protein expression analysis in CD11b+ cells
Strain specific CD89 expression analysis in homozygous B-hCD89 mice by flow cytometry.
Spleen, bone marrow and blood were collected from wild type (WT) mice (+/+) and homozygous B-hCD89 mice (H/H), and analyzed by flow cytometry with species-specific anti-CD89 antibody. Human CD89 was exclusively detectable in CD11b+ cells of homozygous B-hCD89 mice (H/H).
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