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B-hCD44 mice
Strain Name
C57BL/6-Cd44tm1(CD44)Bcgen/Bcgen
Common Name  B-hCD44 mice
Background C57BL/6 Catalog number  110961
Aliases CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1
NCBI Gene ID
12505

Generation of gene editing mouse model and phenotypic analysis


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Strain specific CD44 expression analysis in heterozygous B-hCD44 mice by flow cytometry. Splenocyte were collected from C57BL/6 and heterozygous B-hCD44 mice, and analyzed by flow cytometry with anti-CD44 antibody. Mouse CD44 was detectable in C57BL/6 and heterozygous B-hCD44 mice. Human CD44 was exclusively detectable in heterozygous B-CD44 mice but not WT mice.


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Strain specific CD44 expression analysis in heterozygous B-hCD44 mice by flow cytometry. Splenocyte were collected from C57BL/6 and heterozygous B-hCD44 mice, and analyzed by flow cytometry with anti-CD44 antibody. Mouse CD44 was detectable in C57BL/6 and heterozygous B-hCD44 mice. Human CD44 was exclusively detectable in heterozygous B-CD44 mice but not WT mice.