B-hSOST mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen,drug development,antibody discovery

Please input keywords

Order

*Country

日本

アメリカ

中国

オーストラリア

シンガポール

イギリス

フランス

ドイツ

スイス

イタリア

カナダ

韓国

オランダ

ベルギー

スウェーデン

その他

*Province

*City

*Name

*Telephone

*Company

*Position

*Email

*Verification code

*Verification Code

Home

動物・細胞モデル

Humanized Mouse Models

Cytokine Humanized Mice

Text

B-hSOST mice

Strain Name	C57BL/6-Sost^{tm1(SOST)Bcgen}/Bcgen	Common Name	B-hSOST mice
Background	C57BL/6	Catalog number	110111
Related Genes	SOST (Sclerostin), CDD, DAND61, VBCH
NCBI Gene ID	74499

mRNA expression analysis

from clipboard

Strain specific analysis of SOST gene expression in C57BL/6(+/+) and homozygous B-hSOST mice by RT-PCR.

Mouse Sost mRNA was detectable only in heart and testis of C57BL/6(+/+) mice. Human SOST mRNA was detectable only in homozygous B-hSOST mice, but not in C57BL/6(+/+) mice.

Protein expression analysis

Strain specific analysis of SOST gene expression in C57BL/6(+/+) and homozygous B-hSOST(H/H) mice by western blot.

Heart were collected from C57BL/6(+/+) and homozygous B-hSOST (H/H) mice. SOST was detectable in the heart of the C57BL/6(+/+) and B-hSOST (H/H) mice due to the cross-reactivity of antibodies.