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B-hIL10 mice
Strain Name C57BL/6-Il10tm1(IL10)Bcgen/Bcgen Common Name  B-hIL10 mice
Background C57BL/6 Catalog number

 110060

Related Genes 
IL10 (interleukin 10)
NCBI Gene ID
16153


mRNA expression analysis

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Strain specific analysis of IL10 gene expression in WT and hIL10 mice by RT-PCR. Mouse Il10 mRNA was detectable in splenocytes of wild-type (+/+) mice, Human IL10 mRNA was detectable only in homozygous (H/H) mice but not WT mice. 


Protein expression analysis

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Serum  from both wild type (WT) C57BL/6  and  homozygous B-hIL10 mice were analyzed  by ELISA. 
When treated with LPS, mouse IL10 was only detectable in  WT C57BL/6  mice, while human IL10 was only detectable in homozygous B-hIL10 mice. ND, not detectable. n=3.