|Strain Name||C57BL/6N-Gdf15tm1(GDF15)/Bcgen||Common Name||B-hGDF15 mice|
||growth differentiation factor 15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB|
NCBI Gene ID
mRNA expression analysis
Strain specific analysis of GDF15 gene expression in wild-type mice and B-hGDF15 mice by RT-PCR. Mouse Gdf15 mRNA was detectable in kidney of wild-type (+/+). Human GDF15 mRNA was detectable only in H/H but not in +/+ mice.
Strain specific GDF15 expression analysis in homozygous B-hGDF15 mice by ELISA. Serum was collected from wild-type mice (+/+) and homozygous B-hGDF15 mice (H/H) analyzed by ELISA with species-specific GDF15 ELISA kit. Mouse GDF15 was exclusively detectable in wild-type mice and human GDF15 was exclusively detectable in homozygous B-hGDF15 mice. ND: Not detected.