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B-hCCL22 mice
Strain Name

C57BL/6-Ccl22tm1(CCL22)Bcgen/Bcgen

Common Name  B-hCCL22 mice
Background C57BL/6 Catalog number 110817
Related Genes 

CCL22, A-152E5.1, ABCD-1, DC/B-CK, MDC, 

SCYA22, STCP-1, C-C motif chemokine ligand 22

mRNA expression analysis

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Strain specific analysis of CCL22 gene expression in wild type (WT) mice and B-hCCL22 mice by RT-PCR. Mouse Ccl22 mRNA was detectable only in thymus of WT mice (+/+). Human CCL22 mRNA was detectable only in homozygous B-hCCL22 mice (H/H) but not in WT mice (+/+). 

Protein expression analysis

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Strain specific CCL22 expression analysis in wild type (WT) mice and B-hCCL22 mice by ELISA. Thymus homogenates were collected from WT mice (+/+) and homozygous B-hCCL22 mice (H/H), and analyzed by ELISA with species-specific CCL22 ELISA kit. Mouse CCL22 was detectable in WT mice. Human CCL22 was exclusively detectable in homozygous B-hCCL22 mice (H/H) but not WT mice (+/+) . Values are expressed as mean ± SEM. ND: not detectable.