B-hCDH17 mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen,drug development,antibody discovery

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動物・細胞モデル

Humanized Mouse Models

Other humanized mice

Text

B-hCDH17 mice

Strain Name	C57BL/6-Cdh17^{tm1(CDH17)Bcgen}/Bcgen	Common Name	B-hCDH17 mice
Background	C57BL/6	Catalog number	111593
Aliases	HPT1; CDH16; HPT-1

mRNA expression analysis

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Strain specific analysis of CDH17 gene expression in B-hCDH17 mice by RT-PCR. Mouse Cdh17 mRNA was detectable in colon of wild-type mice (+/+). Human CDH17 mRNA was detectable only in colon of homozygous B-hCDH17 mice (H/H) but not in wild-type mice (+/+).

Protein expression analysis

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CDH17 protein expression analysis in B-hCDH17 mice by Simple Western. Mouse small intestine and colon lysates were analyzed using CDH17-specific antibody. Simple Western lane view with results automatically generated in system software. Human CDH17 was detectable in B-hCDH17 mice (H/H).