B-hALB/hFcRn mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen,drug development,antibody discovery

Strain Name	C57BL/6-Alb^tm1(ALB)Fcgrt^tm1(FCGRT)/Bcgen	Common Name	B-hALB/hFcRn mice
Background	C57BL/6	Catalog number	121805
Aliases	Albumin, Al; Alb1; Alb-1; BCL002;FCGRT(Fc fragment of IgG receptor and transporter)

Protein expression analysis

from clipboard

Strain specific ALB expression analysis in homozygous B-hALB/hFcRn mice by ELISA. Serum was collected from wild-type mice (+/+) and homozygous B-hALB/hFcRn mice (H/H;H/H), and analyzed by ELISA with species-specific ALB ELISA kit. Mouse ALB was detectable in wild-type mice . Human ALB was exclusively detectable in homozygous B-hALB/hFcRn mice but not in wild-type mice. ND: not detected.

from clipboard

Strain specific FcRn expression analysis in homozygous B-hALB/hFcRn mice by western blot. Liver tissue was collected from wild-type C57BL/6 mice (+/+) and homozygous B-hALB/hFcRn mice (H/H;H/H), and analyzed by western blot with anti-FcRn antibody. Mouse FcRn was detectable in wild type mice. Human FcRn was exclusively detectable in homozygous B-hALB/hFcRn mice but not in wild-type C57BL/6 mice.