|
Common name |
B-luc K-562 |
Catalog number | 310673 |
| Aliases |
NA
|
Disease |
Chronic myelogenous leukemia (CML) |
|
Organism |
Human |
Strain | NA |
| Tissue types |
Bone marrow |
Tissue |
Bone marrow |
Description
B-luc K-562 cell line can be used to evaluate anti-cancer drugs in CML in vivo.
Gene targeting strategy for B-luc K-562. The luciferase sequence was inserted in the hAAVS1 locus of wild-type K-562.
Tumor growth and in vivo imaging of B-luc K-562 cells. B-luc K-562 cells (mix, 5x106) were injected by tail vein into B-NDG mice .Signal intensity and body weight were measured twice a week. (A) Imaging was performed on days 0, 4, 7, 11, 21, and 25, (B) Mice body weight (Mean ± SEM). B-luc K-562 cells can be used for in vivo efficacy evaluation.
Quantitative imaging data & body weight changes
