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B-hPDPN mice
Strain Name
C57BL/6N-Pdpntm1(PDPN)Bcgen/Bcgen
Common Name   B-hPDPN mice
Background C57BL/6N Catalog number  111099
Related Genes 
AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, T1A2, TI1A
NCBI Gene ID
14726

Protein expression analysis


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Strain specific PDPN expression analysis in homozygous B-hPDPN mice by western blot. 
Lung tissue was collected from wild-type C57BL/6 mice (+/+) and homozygous B-hPDPN mice (H/H), and analyzed by western blot with anti-PDPN antibody. Mouse PDPN was only detectable in wild-type C57BL/6 mice. Human PDPN was only detectable in homozygous B-hPDPN mice but not in wild type mice.


mRNA expression analysis


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Strain specific analysis of PDPN gene expression in wild-type C57BL/6 mice and B-hPDPN mice by RT-PCR. Mouse Pdpn mRNA was detectable in brain of wild-type C57BL/6 mice (+/+). Human PDPN mRNA was detectable only in homozygous B-hPDPN mice (H/H) but not in wild type mice.