B-hIL2RG mice_Biocytogen Pharmaceuticals (Beijing) Co., Ltd._Biocytogen,drug development,antibody discovery

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動物・細胞モデル

Humanized Mouse Models

Cytokine Humanized Mice

Text

B-hIL2RG mice

Strain Name	C57BL/6N-Il2rg^{tm2(IL2RG)Bcgen}/Bcgen	Common Name	B-hIL2RG mice
Background	C57BL/6N	Catalog number	110087
Related Genes	IL2RG (interleukin-2 receptor subunit gamma)
NCBI Gene ID	16186

Protein expression analysis

Strain specific IL2RG expression analysis in hemizygous B-hIL2RG mice by flow cytometry.

Splenocytes were collected from wild-type C57BL/6 mice (+/+) and hemizygous B-hIL2RG mice (H/Y), and analyzed by flow cytometry with species-specific anti-IL2RG antibody. Mouse IL2RG was detectable in T cells of wild-type mice. Human IL2RG was exclusively detectable in T cells of hemizygous B-hIL2RG mice but not wild-type mice.

Strain specific IL2RG expression analysis in hemizygous B-hIL2RG mice by flow cytometry.

Splenocytes were collected from wild-type C57BL/6 mice (+/+) and hemizygous B-hIL2RG mice (H/Y), and analyzed by flow cytometry with species-specific anti-IL2RG antibody. Mouse IL2RG was detectable in NK cells of wild-type mice. Human IL2RG was exclusively detectable in NK cells of hemizygous B-hIL2RG mice but not wild-type mice.