| Strain Name |
C57BL/6-Ccr4tm1(CCR4)Bcgen/Bcgen
|
Common Name | B-hCCR4 mice |
| Background | C57BL/6 | Catalog number | 170164 |
|
Related Genes |
CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5 | ||
|
NCBI Gene ID |
12773 | ||
mRNA expression analysis
Strain specific analysis of CCR4 gene expression in WT and hCCR4 mice by RT-PCR. Mouse Ccr4 mRNA was detectable only in splenocytes of wild-type (+/+) mice. Human CCR4 mRNA was detectable only in H/H, but not in +/+ mice.
Protein expression analysis in CD4+ T cells
Strain specific CCR4 expression analysis in homozygous B-hCCR4 mice by flow cytometry. Splenocytes were collected from WT and homozygous B-hCCR4 (H/H) mice, and analyzed by flow cytometry with species-specific anti-CCR4 antibody. Mouse CCR4 was detectable in WT mice. Human CCR4 was exclusively detectable in homozygous B-hCCR4 but not WT mice.
Strain specific CCR4 expression analysis in homozygous B-hCCR4 mice by flow cytometry. Splenocytes were collected from WT and homozygous B-hCCR4 (H/H) mice, and analyzed by flow cytometry with species-specific anti-CCR4 antibody. Mouse CCR4 was detectable in WT mice. Human CCR4 was exclusively detectable in homozygous B-hCCR4 but not WT mice.
B-CAG-hCCR4 MC38 bind anti-human CCR4 antibody
